We studied a possible acinar heterogeneity in the transport of organic cations, using rhodamine B as model compound. Employing perfusions of isolated rat livers in the ante-and retrograde mode and quantitative fluorescence microscopy, Zones 1 and 3 were shown to be equally efficient in taking up rho
POSTNATAL DEVELOPMENT OF ORGANIC CATION TRANSPORT IN THE RAT LIVER
✍ Scribed by F. MARTEL; M.J. MARTINS; C. CALHAU; C. HIPÓLITO-REIS; I. AZEVEDO
- Book ID
- 118770491
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 147 KB
- Volume
- 37
- Category
- Article
- ISSN
- 1043-6618
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## Abstract Subcellular organelles from livers of rats three days prenatal to 50 weeks postnatal were separated on sucrose gradients. The peroxisomes had a constant density of 1.243 g/ml throughout the life of the animal. The density of the mitochondria changed from about 1.236 g/ml at birth to a c