Postnatal changes in somatic γ-aminobutyric acid signalling in the rat hippocampus
✍ Scribed by Roman Tyzio; Marat Minlebaev; Sylvain Rheims; Anton Ivanov; Isabelle Jorquera; Gregory L. Holmes; Yuri Zilberter; Yehezkiel Ben-Ari; Rustem Khazipov
- Book ID
- 109027466
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 673 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0953-816X
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## Abstract The RT‐PCR approach was used to estimate the expression of γ‐aminobutyric acid (GABA)~A~ ρ receptor subunits in the hippocampus of neonatal and adult rats. All three ρ subunits were detected at postnatal day (P) 2, the ρ3 subunit being expressed at an extremely low level. The ρ1 and ρ2
Recent data demonstrate weaker g-aminobutyric acid (GABA)-ergic inhibition in ventral (VH) compared with dorsal (DH) hippocampus. Therefore, we examined possible differences regarding the GABA A receptors between VH and DH as follows: 1) the expression of the GABA A receptor subunits (a1/2/4/5, b1/2