Posterior fossa tumors in children with neurofibromatosis type 1 (NF1)
✍ Scribed by Ignacio Pascual-Castroviejo; Samuel I. Pascual-Pascual; Juan Viaño; Fernando Carceller; Manuel Gutierrez-Molina; Carmen Morales; Remedios Frutos-Martinez
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 309 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0256-7040
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Thoracic tumors have been infrequently reported as a complication of neurofibromatosis-1 (NF1). To determine the prevalence and clinical features of thoracic tumors seen in children with NF1, we reviewed medical records and imaging studies for a group of 260 pediatric patients with NF1 followed in a
Short stature and macrocephaly are more common in children with neurofibromatosis 1 (NF1) than in the general population. The cause of these growth alterations is unknown in most cases, but monitoring growth in affected children assists in detection of complications such as optic glioma and hydrocep
## Abstract Neurofibromatosis Type 1 (NF1) is a frequent tumor suppressor gene disorder characterized by multiple benign tumors and high risk of malignancy. Internal tumor burden is a major disease‐associated manifestation and can be most adequately assessed by magnetic resonance imaging of the who