## Abstract ## Background. Because of the impact of nodal status on treatment and survival in squamous cell carcinoma of the head and neck, accurate staging of cervical lymph nodes is critical. This article explores the value of molecular analyses in the detection of cervical lymph node metastasis
Poster 20: T Cell Receptor Analysis of Lymph Node Metastasis in Head and Neck Squamous Cell Carcinoma
โ Scribed by Kenichi Kumagai
- Book ID
- 113738769
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 104 KB
- Volume
- 67
- Category
- Article
- ISSN
- 1531-5053
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๐ SIMILAR VOLUMES
Background. Prognosis of head and neck squamous cell carcinoma (HNSCC) is strongly associated with cervical lymph node metastasis. Cathepsin-D is a lysosomal protease expressed in all cells. Its role in extracellular matrix degradation is postulated to promote tumor invasion and metastasis. Increase
## OBJECTIVE The aim of our study was to assess the feasibility of sentinel lymph node (SLN) radiolocalization in N~0~ neck in squamous cell head and neck carcinoma and its predictive value for occult metastasis. __Study Design__: Nineteen patients of an open prospective trial. ## SETTING After