Sentinel lymph node evaluation in squamous cell carcinoma of the head and neck

✍ Scribed by Sandro J. Stoeckli; H. Steinert; M. Pfaltz; Stephan Schmid

• Book ID: 117843691
• Publisher: SAGE Publications
• Year: 2001
• Tongue: English
• Weight: 142 KB
• Volume: 125
• Category: Article
• ISSN: 0194-5998
• DOI: 10.1067/mhn.2001.118074

✦ Synopsis

OBJECTIVE

The aim of our study was to assess the feasibility of sentinel lymph node (SLN) radiolocalization in N~0~ neck in squamous cell head and neck carcinoma and its predictive value for occult metastasis.

Study Design: Nineteen patients of an open prospective trial.

SETTING

After peritumoral injection of a 99m Tc labeled radiocolloid, the SLN was localized preoperatively by lymphoscintigraphy and intraoperatively through the intact skin by a hand‐held gamma‐probe. The histology of the SLN and the nodes of the elective neck dissection were compared.

RESULTS

Localization of the SLN by lymphoscintigraphy was possible in 18 of 19, and with the handheld gamma‐probe in all 19 patients. Six SLN revealed occult metastatic disease. No skip metastasis were found in the 13 neck specimen with negative SLN.

CONCLUSION

SLN evaluation in N~0~ neck in squamous cell carcinoma of the head and neck is accurately feasible and seems to adequately predict the presence of occult metastasis.