Tumor-induced osteomalacia originating f
β
Kenya Kobayashi; Kazunari Nakao; Kensuke Kawai; Ken Ito; Seiji Hukumoto; Takahir
π
Article
π
2010
π
John Wiley and Sons
π
English
β 270 KB
π 1 views
Background. Tumor-induced osteomalacia (TIO) is a rare clinical entity in which secondary osteomalacia is induced by tumor-related products. Fibroblast growth factor 23 (FGF-23) mRNA is overexpressed in the tumor tissue, leading to impaired reabsorption of phosphorus in the renal tubules and hypopho