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Antacid-induced osteomalacia: a case report with a histomorphometric analysis

✍ Scribed by Dr. M. KASSEM; E. F. ERIKSEN; F. MELSEN; L. MOSEKILDE

Book ID
114742037
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
819 KB
Volume
229
Category
Article
ISSN
0954-6820

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Background. Tumor-induced osteomalacia (TIO) is a rare clinical entity in which secondary osteomalacia is induced by tumor-related products. Fibroblast growth factor 23 (FGF-23) mRNA is overexpressed in the tumor tissue, leading to impaired reabsorption of phosphorus in the renal tubules and hypopho