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Poster #110 NO ASSOCIATION BETWEEN SNAP-25 GENE POLYMORPHISMS AND WEIGHT GAIN IN ANTIPSYCHOTIC TREATMENT OF SCHIZOPHRENIA

✍ Scribed by Aziz Ferchiou; Anne Dumaine Mohamed Lajnef; Christophe Laçon; Pierre Michel Llorca; Stephane Jamain; Marion Leboyer; Alexandre Méary


Book ID
119558394
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
73 KB
Volume
136
Category
Article
ISSN
0920-9964

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## Abstract ## Objective Atypical antipsychotic drugs, in particular clozapine and olanzapine, influence cellular lipogenesis and are associated with metabolic side effects including weight gain. Insulin induced gene 2 (INSIG2) mediates feedback control of lipid synthesis and polymorphisms in the