Post-Traumatic Stress Disorder: Basic Science and Clinical Practice

✍ Scribed by Terence M. Keane, Brian P. Marx, Denise M. Sloan (auth.), Joseph E. LeDoux, Terrence Keane, Peter Shiromani (eds.)

• Publisher: Humana Press
• Year: 2009
• Tongue: English
• Leaves: 400
• Edition: 1
• Category: Library

✦ Synopsis

Post-traumatic stress disorder is a psychiatric condition that can occur in anyone who has experienced a life-threatening or violent event. The trauma can be due to war, terrorism, torture, natural disasters, accidents, violence, or rape. In Post-Traumatic Stress Disorder: Basic Science and Clinical Practice, widely regarded experts in the field outline the neurobiology of post-traumatic stress disorder (PTSD) and provide a range of state-of-the-art treatment strategies for clinicians. Originally associated exclusively with military service, PTSD is now recognized as a disorder that can result from any traumatic situation and can afflict children as well as adults. In this ground-breaking title, the authors review the current state of knowledge of PTSD, covering not only pharmacological and psychological treatment strategies but also epidemiological findings, the neurobiology and neurophysiology of PTSD, and brain imaging issues. In all, Post-Traumatic Stress Disorder: Basic Science and Clinical Practice provides today's most relevant and up-to-date information regarding the treatment and understanding of those affected by PTSD and is an invaluable resource for all clinicians and neuroscientists concerned with the condition

✦ Table of Contents

Front Matter....Pages i-xiii
Front Matter....Pages 1-1
Post-Traumatic Stress Disorder: Definition, Prevalence, and Risk Factors....Pages 1-19
The Amygdala and the Neural Pathways of Fear....Pages 23-38
Physiology of the Amygdala: Implications for PTSD....Pages 39-78
Counteracting Molecular Pathways Regulating the Reduction of Fear: Implications for the Treatment of Anxiety Diseases....Pages 79-103
Memory in PTSD:A Neurocognitive Approach....Pages 105-130
Front Matter....Pages 1-1
Toward Animal Models of Post-Traumatic Stress Disorder....Pages 133-149
PTSD: From Neurons to Networks....Pages 151-184
Front Matter....Pages 1-1
Arousal Neurons in the Brain....Pages 187-200
Hyperarousal and Post-Traumatic Stress Disorder: A Role for the Hypocretin System....Pages 201-211
The Locus Coeruleus-Noradrenergic System and Stress: Implications for Post-Traumatic Stress Disorder....Pages 213-230
Effect of Stress on Sleep and Its Relationship to Post-Traumatic Stress Disorder....Pages 231-253
Front Matter....Pages 1-1
Stress Hormones and PTSD....Pages 257-275
Low Basal Cortisol and Startle Responding as Possible Biomarkers of PTSD: The Influence of Internalizing and Externalizing Comorbidity....Pages 277-293
Front Matter....Pages 1-1
Functional Neuroimaging in Post-Traumatic Stress Disorder....Pages 297-317
The Amygdala in Post-Traumatic Stress Disorder....Pages 319-334
Front Matter....Pages 1-1
Pharmacologic Treatment of PTSD....Pages 337-361
Guided Imagery as a Therapeutic Tool in Post-Traumatic Stress Disorder....Pages 363-373
Virtual Reality Exposure Therapy for Combat-Related PTSD....Pages 375-399
Back Matter....Pages 401-409

✦ Subjects

Psychiatry; Neurosciences; Neurology