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Post-translational modifications of adiponectin: mechanisms and functional implications

✍ Scribed by Wang, Yu; Lam, Karen S. L.; Yau, Ming-hon; Xu, Aimin


Book ID
120285102
Publisher
Portland Press
Year
2008
Tongue
English
Weight
632 KB
Volume
409
Category
Article
ISSN
0264-6021

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Post-translational modifications of self
✍ Stephen M Anderton 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 123 KB

Alterations in amino acid sequence can generate neo-epitopes from self proteins, causing autoaggressive immune attack. There is a range of possible post-translational modifications (PTMs) of mammalian proteins that can allow immune recognition of neo-self epitopes. These effects can vary from overt