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Post-translational control of human hemoglobin synthesis The role of the differential affinity between globin chains in the control of mutated globin gene expression

✍ Scribed by Fulvio Mavilio; Marino Marinucci; Raffaella Guerriero; Gino Cappellozza; Leonardo Tentori


Book ID
115747344
Publisher
Elsevier Science
Year
1980
Weight
837 KB
Volume
610
Category
Article
ISSN
0005-2787

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## Abstract PKCΞ± was found to be expressed (mRNA and protein) throughout the in vitro maturation of primary human erythroblasts but its activity (phosphorylation levels and nuclear localization) was consistently higher in cells derived from human neonatal rather than adult blood. Since the Ξ³/γ + β