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Post-transcriptional and post-translational regulation of Bcl2

✍ Scribed by Willimott, Shaun; Wagner, Simon D.

Book ID
117990812
Publisher
Portland Press
Year
2010
Tongue
English
Weight
152 KB
Volume
38
Category
Article
ISSN
0300-5127

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## Abstract PTEN is a critical tumor suppressor gene mutated frequently in various human cancers. Previous studies have showed that PTEN mRNA expression is down‐regulated by TGF‐β1 in various cell lines. In present study, we have found that TGF‐β1 down‐regulates PTEN mRNA and protein expression in