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Post operative stimulation of cell mediated immunity

✍ Scribed by Smith, J. A. R. ;Hendry, W. S. ;Duncan, J. L. ;Norman, J. N.

Publisher
Springer-Verlag
Year
1985
Tongue
English
Weight
1019 KB
Volume
63
Category
Article
ISSN
1432-1440

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The effects of phenytoin on cellular immunity were examined in murine models. Fresh splenocytes were obtained from mice which had received 1 mg/day of phenytoin i.p. for 28 days. The serum concentration of phenytoin in these animals was 10-20 micrograms/ml. The proliferative response of splenocytes