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Possible involvement of presynaptic 5-HT autoreceptors in effect of lithium on 5-HT release in hippocampus of rat

✍ Scribed by I. Hotta; S. Yamawaki


Book ID
118955888
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
638 KB
Volume
27
Category
Article
ISSN
0028-3908

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Subclassification of presynaptic 5-HT au
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Human cerebral cortical synaptosomes were used to determine the 5-hydroxytryptamine (5-HT) receptor subtype to which the inhibitory presynaptic 5-HT autoreceptor belongs. The synaptosomes preincubated with [3H~5-HT were superfused and tritium overflow was stimulated by high K +. The K +-evoked triti