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Possible induction of fatty acid cyclooxygenase in mouse osteoblastic cells (MC3T3-E1) by cAMP

✍ Scribed by Masami Kusaka; Takeo Oshima; Kazushige Yokota; Shozo Yamamoto; Masayoshi Kumegawa


Book ID
117046875
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
606 KB
Volume
972
Category
Article
ISSN
0005-2728

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## Abstract Statins inhibit 3‐hydroxy‐3‐methylglutaryl‐coenzyme A (HMG‐CoA) reductase, which catalyzes conversion of HMG‐CoA to mevalonate, a rate‐limiting step in cholesterol synthesis. The present study was undertaken to understand the events of osteoblast differentiation induced by statins. Simv