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Possible implications of CpG avoidance in the flatwormSchistosoma mansoni

✍ Scribed by Héctor Musto; Helena Rodríguez-Maseda; Fernando Alvarez; José Tort

Publisher
Springer
Year
1994
Tongue
English
Weight
424 KB
Volume
38
Category
Article
ISSN
0022-2844

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✦ Synopsis

We report the analysis of the biases of CpG, TpG, and CpA of all the DNA sequences data from the Trematode Schistosoma mansoni. Our resuits show CpG avoidance whereas TpG and CpA frequencies are over the expected values. These characteristics are similar to the biases displayed by methylated genomes, but in platyhelminths 5mC has not been detected by biochemical methods. The possible implications of this CpG shortage are discussed.

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