We report the analysis of the biases of CpG, TpG, and CpA of all the DNA sequences data from the Trematode Schistosoma mansoni. Our resuits show CpG avoidance whereas TpG and CpA frequencies are over the expected values. These characteristics are similar to the biases displayed by methylated genomes
Compositional correlations in the nuclear genes of the flatwormSchistosoma mansoni
✍ Scribed by Héctor Musto; Helena Rodríguez-Maseda; Fernando Alvarez
- Publisher
- Springer
- Year
- 1995
- Tongue
- English
- Weight
- 337 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0022-2844
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✦ Synopsis
We have investigated the genome organization in the flatworm Schistosoma mansoni. First, we analyzed the compositional distributions of the three codon positions. Second, we investigated the correlations that exist between (1) the GC levels of exons against flanking regions, (2) the GC levels of third codon positions against flanking regions, (3) the dinucleotide frequencies of exons against flanking regions, and (4) the GC levels of 5' against 3' regions. The modality of the distribution of third codon positions, together with the significant correlations found, leads us to propose that the nuclear genome of this species is compositionally compartmentalized.
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