Possibility of simultaneous apparenlc zero- and first-order kinetics in the in vivo formation of a single drug metabolite

Kinetic analysis of a single-path, and o

Kinetic analysis of a single-path, and of a dual-path, sequence of four first-order reactions. The reactions of dibenzoylmesitylene and acetylbenzoylmesitylene in sulfuric acid

✍ Jameel A. Farooqi; Peter H. Gore; David N. Waters; Gerald F. Moxon 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 311 KB

Dibenzoylmesitylene undergoes protiodeacylation in 89.8% (w/w) sulfuric acid at ca. 9O"C, with subsequent sulfonation, to give mesitylenedisulfonic acid. The reaction involves a single-path sequence of four first-order reactions. The corresponding reaction of acetylbenzoylmesitylene can proceed by t