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Positron emission tomography studies using 11C-labeled L-DOPA

✍ Scribed by Watanabe, Yasuyoshi; Hartvig, Per; Bjurling, Peter; Oka, Shogo; Tanemura, Mihoko; Miwa, Soichi; Långström, Bengt


Book ID
122349394
Publisher
Elsevier Science
Year
1990
Weight
107 KB
Volume
11
Category
Article
ISSN
0921-8696

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The present study describes a rapid synthesis method for labeled [ 11 C]FK506 for positron emission tomography (PET). A one-pot reaction from [ 11 C]CH 3 I, involving a Wittig reaction as the key carbon carbon bond formation was developed. The chemical process was accomplished using a designed, full