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Positive selection of Tcrb-V4+CD8+T cells by H-2dmolecules

โœ Scribed by Kyuhei Tomonari; Sue Fairchild


Book ID
104655715
Publisher
Springer-Verlag
Year
1990
Tongue
English
Weight
240 KB
Volume
32
Category
Article
ISSN
0093-7711

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๐Ÿ“œ SIMILAR VOLUMES


Positive selection of Tcrb-V10b+T cells
โœ Kyuhei Tomonari; Rosemari Hederer; Hans Hengartner ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 596 KB

The Tcrb-V10b+ T cell population has been examined with a newly established antibody, KT10b, specific for Tcrb-V10b but not Tcrb-V10a. H-2E+ mice have higher levels of Tcrb-V10b+ T cells (4.3%-11.0%) than H-2E- mice (2.2%-4.9%). This difference appears to be determined by levels of Tcrb-V10b+ T cell

Positive and negative selection of Tcrb-
โœ Kyuhei Tomonari; Sue Fairchild ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 672 KB

Tcrb-V6+ T cells are deleted by an endogenous superantigen probably encoded by a mouse mammary tumor provirus (Mtv), Mtv-7, in association with major histocompatibility complex (MHC) class II molecules. In contrast, Tcrb-V6+CD4+ T cells are positively selected by MHC class II E molecules in Mtv-7- m

Negative selection of Tcra-V8+CD8+T cell
โœ Kyuhei Tomonari ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 349 KB

Tcrb-V-specific positive and negative selection of T cells has been well documented. In contrast, nothing is known about Tcra-V-specific selection. Using Tcra-V8-specific KT50 antibody Tcra-V8-specific selection of T cells has been examined. The CD8+ T cell subpopulation bearing Tcra-V8 are shown to