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Positive modulation of glutamatergic receptors potentiates the suppressive effects of antipsychotics on conditioned avoidance responding in rats

✍ Scribed by Christina Kurre Olsen; Mads Kreilgaard; Michael Didriksen

Book ID
113841049
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
259 KB
Volume
84
Category
Article
ISSN
0091-3057

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The effects of the enantiomers of 3-PPP on the maintenance of conditioned avoidance responding (CAR) were studied. The weak classical dopamine (DA) agonist (+)-3-PPP failed to interfere with CAR at any dose tested (0.8-13.6 mg/kg). Low doses of the drug produced sedation, while high doses produced b