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Positive- and negative-regulation of Ca2+ entry through ACh receptor channels by phosphorylation

✍ Scribed by Tomoyuki Nishizaki; Toshiyuki Matsuoka; Katumi Sumikawa


Book ID
117387326
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
477 KB
Volume
69
Category
Article
ISSN
0169-328X

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Calcium channels in the heart play a major role in cardiac function. These channels are modulated in a variety of ways, including protein phosphorylation. Cyclic AMP-mediated phosphorylation is the best understood phosphorylation mechanism which regulates calcium influx into cardiac cells. Binding o