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Positive and negative regulation of Raf kinase activity and function by phosphorylation

✍ Scribed by Chong, H.


Book ID
111748017
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
422 KB
Volume
20
Category
Article
ISSN
0261-4189

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Positive and negative regulation of Src-
✍ Matthew L Thomas; Eric J Brown πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 English βš– 186 KB

D45 is the major transmembrane tyrosine phosphatase of the immune system and is highly expressed by all hematopoietic cells 1 . The best described role for CD45 is in antigen receptor signal transduction. In this case, the phosphatase activity of CD45 appears to be required for activation of Src-fam