๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Positionally cloned susceptibility genes in allergy and asthma

โœ Scribed by Juha Kere; Tarja Laitinen

Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
121 KB
Volume
16
Category
Article
ISSN
0952-7915

No coin nor oath required. For personal study only.

โœฆ Synopsis

After several years of research to find asthma-susceptibility genes using genome-wide linkage scans and refined genetic mapping methods, four highly interesting candidate genes have recently been reported. Each of these genes represents a different functional class, and might point to a new pathway in the pathogenesis of asthma. Current research is focusing on confirming the genetic associations in diverse populations and understanding the biochemical functions of the proteins. These second-generation candidate genes for asthma susceptibility will stimulate much research, and might also enable the testing of multigenic models with sufficiently large sample sets.

๐Ÿ“œ SIMILAR VOLUMES

Genetic polymorphism in allergy and asth
Genetic polymorphism in allergy and asthma
โœ Donata Vercelli ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 103 KB

The impact of genetic factors on the pathogenesis of allergy and asthma is currently an area of intense investigation. Although epidemiological studies find more and more genes that are likely to contribute to allergic inflammation, functional studies of the mechanisms that link genetic variation wi

Asthma and allergy in New Zealand farmer
Asthma and allergy in New Zealand farmers
โœ M. Kimbell-Dunn; L. Bradshaw; T. Slater; R. Erkinjuntti-Pekkanen; D. Fishwick; N ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 89 KB ๐Ÿ‘ 2 views

## Aims To examine the prevalence of symptoms of asthma and allergy in different farming groups in New Zealand. Methods A postal questionnaire was sent to a random sample of 2,500 farmers throughout New Zealand. Results The response rate was 77% (1,706 of 2,203 eligibles). The 12-month period prev

Role of regulatory T cells in allergy an
Role of regulatory T cells in allergy and asthma
โœ Omid Akbari; Philippe Stock; Rosemarie H DeKruyff; Dale T Umetsu ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 196 KB

Th2 cells play a critical role in the pathogenesis of allergy and asthma. However, the immunological mechanisms that downmodulate and protect against the development of these disorders are poorly understood. A spectrum of CD4 รพ T cells, including Th3 cells, T R cells, CD4 รพ CD25 รพ cells and NKT cell