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Positional identification of Ncf1 as a gene that regulates arthritis severity in rats

✍ Scribed by Olofsson, Peter; Holmberg, Jens; Tordsson, Jesper; Lu, Shemin; Åkerström, Bo; Holmdahl, Rikard


Book ID
109918158
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
793 KB
Volume
33
Category
Article
ISSN
1061-4036

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Objective. To identify novel non-major histocompatibility complex (non-MHC) genetic loci controlling the severity of homologous rat type I1 collagen-induced arthritis (CIA). Methods. We conducted a genome-wide scan to identify CLA regulatory quantitative trait loci (QTL) in an F, cross between DA (