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Porphyrins with exocyclic rings. Part 8. Synthesis of nitrogen-15 and carbon-13 labeled 2,3:7,8:12,13:17,18-tetrabutanoporphyrin

✍ Scribed by Shaohua Chen; Timothy D. Lash

Publisher
Journal of Heterocyclic Chemistry
Year
1997
Tongue
English
Weight
441 KB
Volume
34
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

Nitrogen‐15 labeled butyl 4,5,6,7‐tetrahydro‐2__H__‐isoindoIe‐1‐carboxylate was prepared via butyl iso‐cyanoacetate from ^15^N‐glycine in an overall 46% yield. This bicyclic intermediate was converted into nitrogen‐15 and carbon‐13 labeled 2,3:7,8:12,13:17,18‐tetrabutanoporphyrin, a useful model system for the sedimentary tetrahydrobenzoporphyrins.

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