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Porphyrin-linked oligonucleotides: Synthesis and sequence-specific modification of ssDNA

✍ Scribed by E.I. Frolova; E.M. Ivanova; V.F. Zarytova; T.V. Abramova; V.V. Vlassov


Book ID
115923933
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
821 KB
Volume
269
Category
Article
ISSN
0014-5793

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## Abstract ## Background Single‐stranded oligonucleotides (ssODN) can induce site‐specific genetic alterations in selected mammalian cells, but the involved mechanisms are not known. ## Methods We corroborate the potential of genomic sequence correction by ssODN using chromosomally integrated m