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Porous silicon-based scaffolds for tissue engineering and other biomedical applications

✍ Scribed by Coffer, Jeffery L. ;Whitehead, Melanie A. ;Nagesha, Dattatri K. ;Mukherjee, Priyabrata ;Akkaraju, Giridhar ;Totolici, Mihaela ;Saffie, Roghieh S. ;Canham, Leigh T.

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
162 KB
Volume
202
Category
Article
ISSN
0031-8965

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✦ Synopsis

Abstract

This work describes the formation of porous composite materials based on a combination of bioactive mesoporous silicon and bioerodible polymers such as poly‐caprolactone (PCL). The fabrication of a range of composites prepared by both salt leaching and microemulsion techniques are discussed. Particular attention to the influence of Si content in the composite on in vitro calcification assays are assessed. For each system, cytotoxicity and cellular proliferation are explicitly evaluated through fibroblast cell culture assays. (© 2005 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)

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