✦ LIBER ✦

Porokeratosis of Mibelli: Successful treatment with topical 5% imiquimod cream

✍ Scribed by Shannon Harrison; Rodney Sinclair

Publisher: John Wiley and Sons
Year: 2003
Tongue: English
Weight: 754 KB
Volume: 44
Category: Article
ISSN: 0004-8380
DOI: 10.1046/j.1440-0960.2003.00010.x

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✦ Synopsis

SUMMARY

A 77‐year‐old woman with a large porokeratosis of Mibelli on the left shin was successfully treated with topical 5% imiquimod cream applied to the entire lesion once daily without occlusion three times a week. A strong inflammatory reaction was achieved in 6 weeks of treatment. The lesion had been present for approximately 6 years and prior treatments included curettage and electrocautery, cryotherapy and topical 5‐fluorouracil under occlusion. At the end of treatment with topical 5% imiquimod cream, punch biopsy was negative for porokeratosis. The lesion healed without scarring. At 24‐month follow up there had been no sign of clinical recurrence.

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