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PopulationIn Vitro-In VivoCorrelation Model for Pramipexole Slow-Release Oral Formulations

✍ Scribed by Elena Soto; Sebastian Haertter; Michael Koenen-Bergmann; Alexander Staab; Iñaki F. Trocóniz


Book ID
106493686
Publisher
Springer US
Year
2009
Tongue
English
Weight
296 KB
Volume
27
Category
Article
ISSN
0724-8741

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The objective of the current study was to develop and evaluate the internal predictability for level C and A in vitro±in vivo correlation (IVIVC) models for prototype modi®ed-release (MR) dosage forms of metformin. In vitro dissolution data for metformin were collected for 22 h using a USP II (paddl