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Population variation at the polymorphic ApaLI restriction enzyme site in intron 5 of the WT1 gene

✍ Scribed by Corinne Besnard-Guérin; Robert Winqvist; Irene Newsham; Webster K. Cavenee


Book ID
115091875
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
378 KB
Volume
50
Category
Article
ISSN
0009-9163

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✍ Hiroshi Inaba; Michio Fujimaki; Haig H. Kazazian; Stylianos E. Antonarakis 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 112 KB

A novel MspI DNA polymorphic site has been found in intron 22 of the human factor VIII gene. This site is informative almost exclusively in the Japanese population (heterozygosity 0.45) and will be of considerable importance in carrier detection and prenatal diagnosis of hemophilia A in this populat