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Population pharmacokinetics of midazolam in neonates

✍ Scribed by Burtin, Pascale; Jacqz-Aigrain, Evelyne; Girard, Pascal; Lenclen, Richard; Magny, Jean-François; Betremieux, Pierre; Tehiry, Cédric; Desplanques, Laurence; Mussat, Philippe

Book ID
109845359
Publisher
Nature Publishing Group
Year
1994
Tongue
English
Weight
876 KB
Volume
56
Category
Article
ISSN
0009-9236

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Midazolam is a water soluble benzodiazepine, with a short elimination half-life in adults and children. An IV bolus (0.2 mg.kg-1) immediately followed by continuous infusion of 0.06 mg.kg-1.h-1 was administered to 15 critically ill neonates at a gestational age of 32.8 weeks, who required sedation f