The bispecific monoclonal antibody (biMAb) OC/TR combines the anti-ovarian-cancer reactivity of the MOvl8 monoclonal antibody (MAb) with the reactivity of an anti-CD3 MAb. Pre-clinical studies have indicated that this biMAb is able to redirect the cytolytic activity of T cells towards tumour cells,
Population pharmacokinetics of antifibroblast activation protein monoclonal antibody F19 in cancer patients
β Scribed by Paul Tanswell; Pilar Garin-Chesa; Wolfgang J. Rettig; Sydney Welt; Chaitanya R. Divgi; Ephraim S. Casper; Ronald D. Finn; Steven M. Larson; Lloyd J. Old; Andrew M. Scott
- Book ID
- 108640053
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 83 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0306-5251
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Ovarian cancer is a highly malignant tumor of mainly postmenopausal women. The long-term prognosis of this malignancy is largely determined by micrometastasis present at the time of second-look surgery. In general, patients face a poor outcome. New radio-immunoscintigraphic methods to target tumor t
## Abstract We investigated the difference in osteoclast formation between patients with osteoporosis and two healthy control groups by inducing it from peripheral blood monocytes with use of antiβfusion regulatory proteinβ1 monoclonal antibody. The group of patients with osteoporosis consisted of
An enzyme immunoassay system that measures cryptic epitopes on breast cancer mucinlike antigens (BCM-EIA) was evaluated in a double-blind manner in sera from 58 normal blood donors, 36 sex-and age-matched controls, 36 patients with benign breast diseases, and 47 patients with breast cancer. Two muri
3'I-labelled HMFGl or HMFGl F(ab')2 monoclonal antibody (MAb) was administered intraperitoneally to I S patients with epithelial ovarian cancer who had completed chemotherapy and were in complete or good partial remission. Each patient received 2-3 mCi. Patients were scanned immediately after and un