𝔖 Bobbio Scriptorium
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Population Pharmacokinetic/Pharmacodynamic Analyses as the Basis for Dosing of Therapeutic Monoclonal Antibodies

✍ Scribed by Dr Bernd Meibohm

Book ID
119931369
Publisher
Springer International Publishing AG
Year
2011
Tongue
English
Weight
89 KB
Volume
50
Category
Article
ISSN
0312-5963

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Postmenopausal patients with metastatic breast cancer were treated with medroxyprogesterone acetate (MPA) (Clinovir) in dosages between 500 and 1500 mg orally per day. The relation of MPA plasma concentrations and endocrine effects were studied in a longitudinal fashion. MPA exerted suppressive effe