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Population pharmacokinetic and pharmacodynamic modelling of artemisinin and mefloquine enantiomers in patients with falciparum malaria

✍ Scribed by Ulrika S. Svensson; Mohamed Alin; Mats O. Karlsson; Yngve Bergqvist; Michael Ashton


Publisher
Springer
Year
2002
Tongue
English
Weight
296 KB
Volume
58
Category
Article
ISSN
0031-6970

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Pharmacokinetics of halofantrine and n-d
✍ J. R. Veenendaal; A. D. Parkinson; N. Kere; K. H. Rieckmann; M. D. Edstein πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 430 KB

Halofantrine is a new blood schizontocidal drug used for the treatment of multidrug-resistant falciparum malaria. The pharmacokinetics of halofantrine (HAL) and its principal metabolite, N-desbutylhalofantrine (BHAL), was investigated in 6 adult male patients of Melanesian origin with uncomplicated