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Pooled analysis of phase III clinical studies of palonosetron versus ondansetron, dolasetron, and granisetron in the prevention of chemotherapy-induced nausea and vomiting (CINV)

โœ Scribed by Schwartzberg, Lee; Barbour, Sally Y.; Morrow, Gary R.; Ballinari, Gianluca; Thorn, Michael D.; Cox, David


Book ID
121579303
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
316 KB
Volume
22
Category
Article
ISSN
0941-4355

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## Background: Palonosetron, a highly selective and potent 5-ht(3) receptor antagonist with a strong binding affinity and a long plasma elimination half-life (approximately 40 hours), has shown efficacy in phase ii trials in preventing chemotherapy-induced nausea and vomiting (cinv) resulting from