Randomized, double-blind, crossover study of palonosetron compared with granisetron for the prevention of chemotherapy-induced nausea and vomiting in a Chinese population
โ Scribed by Weihua Tian; Zhiqiang Wang; Juntian Zhou; Shucai Zhang; Jinghui Wang; Qiang Chen; Cheng Huang; Liangxi Pan; Lili Zhang; Jianjin Huang; Hong Shen; Tongyu Lin
- Publisher
- Springer US
- Year
- 2010
- Tongue
- English
- Weight
- 246 KB
- Volume
- 28
- Category
- Article
- ISSN
- 1357-0560
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Background. A single-institution, prospective, randomized open trial was performed to compare ondansetron and granisetron in the prevention of chemotherapyrelated nausea and vomiting. The effect of antemetic drugs was analyzed indipendently for patients treated with highly emetogenic chemotherapy (S
## Purpose A novel transdermal formulation of granisetron (the granisetron transdermal delivery system (GTDS)) has been developed to deliver granisetron continuously over 7ย days. This double-blind, phase III, non-inferiority study compared the efficacy and tolerability of the GTDS to daily oral gra