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Pontin and reptin: Two novel regulators of the transcriptional response to hypoxia

✍ Scribed by Joel I. Perez-Perri; Matthew Cockman; Andrés Dekanty; Peter J. Ratcliffe; Pablo Wappner

Book ID
118505649
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
127 KB
Volume
356
Category
Article
ISSN
0012-1606

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## Abstract ## Objective Hypoxia is a prominent feature in rheumatoid arthritis (RA) synovium. However, its contribution to the pathogenesis of RA remains unclear. We undertook this study to systematically characterize the changes in gene expression induced by hypoxia in synovial fibroblasts. ##