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Genetic amplification of the transcriptional response to hypoxia as a novel means of identifying regulators of angiogenesis

โœ Scribed by Jonathan Richard White; Robert A Harris; Sheena R Lee; Marie H Craigon; Katie Binley; Toby Price; Georgina L Beard; Christopher R Mundy; S Naylor

Book ID
117592355
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
301 KB
Volume
83
Category
Article
ISSN
0888-7543

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## Abstract Vascular endothelial growth factor (VEGF) and angiopoietins regulate endothelial cell survival and migration and are essential for angiogenesis. Considerable progress has been made towards understanding hypoxiaโ€mediated regulation of VEGF and its receptors. In contrast, little is known