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PON1 Q192R and L55M Polymorphisms and Organophosphate Toxicity Risk: A Meta-Analysis

✍ Scribed by You, Tian; Lv, Jingyu; Zhou, Liping

Book ID
121277231
Publisher
Mary Ann Liebert
Year
2013
Tongue
English
Weight
398 KB
Volume
32
Category
Article
ISSN
1044-5498

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## Abstract Paraoxonase 1 (PON 1) is a high‐density lipoprotein (HDL)‐associated enzyme with antioxidant function protecting low‐density lipoprotein (LDL) from oxidation. PON 1 has two amino acid polymorphisms in coding region; L/M 55 and Q/R 192. These polymorphisms modulate paraoxonase activity o