Polyvalent pneumococcal immunization of patients with plasma cell dyscrasias
β Scribed by Richard A. Shildt; Ronald R. Rubin; Gerald Schiffman; Paul Giolma
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 304 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0008-543X
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π SIMILAR VOLUMES
A patient with hairy cell leukemia experienced two episodes of an unusual neurologic disturbance associated with vaccination. The association with polyvalent pneumococcal vaccine has not previously been noted.
## Abstract ## BACKGROUND To the authors' knowledge, the prevalence of vitamin B12 deficiency among patients with plasma cell dyscrasias (PCD) is largely unknown. Identifying this vitamin deficiency in such patients could help improve their anemia and increase their tolerance to potentially neurot
Fifty-nine percent of 49 patients with motor neuron disease and 25% of 91 control subjects had IgM antibodies to ganglioside GM1 but usually not to GDlb at titers less than 1:80. This suggests that antibodies to GM1 may be part of the normal human antibody repertoire. However, given the higher incid