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Polyunsaturated fatty acids reduce pyrogen-induced tissue factor expression in human monocytes

✍ Scribed by A. Lalé; J.M. Herbert

Book ID: 115783830
Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 336 KB
Volume: 48
Category: Article
ISSN: 0006-2952
DOI: 10.1016/0006-2952(94)90118-x

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Tissue factor (TF) is a glycoprotein which acts as a trigger of the coagulation cascade. TF expression may be induced at the surface of monocytes and endothelial cells by several stimuli including bacterial endotoxin U S ) and cytokines (IL1 p, TNFa) and there is a large body of evidence for the inv