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Polyubiquitination of the neurotrophin receptor p75 directs neuronal cell survival

✍ Scribed by Thangiah Geetha; Chen Zheng; Bradford Unroe; Marina Sycheva; Heidi Kluess; Jeganathan Ramesh Babu

Book ID
116303301
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
493 KB
Volume
421
Category
Article
ISSN
0006-291X

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## Abstract The p75 neurotrophin receptor (p75^NTR^), a common receptor for members of the neurotrophins (NT) family, was previously identified as a molecular determinant of brain metastasis. We have also reported that NT treatment of murine and human brain‐metastatic melanoma cells affects their i