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Mesenchymal and Neuronal Cell Expression of the p75 Neurotrophin Receptor Gene Occur by Different Mechanisms

✍ Scribed by L.Julie Huber; Moses V. Chao


Book ID
115597304
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
992 KB
Volume
167
Category
Article
ISSN
0012-1606

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## Abstract Neuronal pathology of the brain with Alzheimer's disease (AD) is characterized by numerous depositions of amyloid‐β peptides (AΞ²). AΞ² binding to the 75‐kDa neurotrophin receptor (p75NTR) causes neuronal cell death. Here we report that AΞ² causes cell death in neuronal hybrid cells transf