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Polysialyltransferases: major players in polysialic acid synthesis on the neural cell adhesion molecule

✍ Scribed by Kiyohiko Angata; Minoru Fukuda


Book ID
117456861
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
555 KB
Volume
85
Category
Article
ISSN
0300-9084

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The polysialic acid modification of the
✍ C.G. Becker; A. Artola; R. Gerardy-Schahn; T. Becker; H. Welzl; M. Schachner πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 959 KB

The a-2,Slinked polysialic acid (PSA) modification of the neural cell adhesion molecule (NCAM) modulates morphogenetic cell interactions. PSA is strongly expressed during neural development and generally down-regulated in the adult. However, it remains prominent in some areas of the brain, e.g., the