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Polysaccharides from Cannabis sativa active in lowering intraocular pressure

โœ Scribed by Linda C. Hodges; Howard M. Deutsch; Keith Green; Leon H. Zalkow


Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
577 KB
Volume
5
Category
Article
ISSN
0144-8617

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An alkaloidal extract (ALKS1) from Troph
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A 1.0% solution of ALKS1, an alkaloidal extract obtained from Trophis racemosa, produced a significant fall in intraocular pressure in the dog's eye (p < 0.001). The fall was antagonized by atropine (p < 0.0025), suggesting ALKS1 is acting through a muscarinic mode of action. Further purifcation of