โ Scribed by Boyd Koffman; Larry Junck; Stanton B. Elias; Howard W. Feit; Steven R. Levine
No coin nor oath required. For personal study only.
We present three new and 14 retrospective cases of polyradiculopathy in sarcoidosis. Of these, 71% had weakness and 59% areflexia of the lower extremities, and 35% had sphincter dysfunction. Cases often were associated with central nervous system sarcoidosis. All cases involved thoracolumbar or lumbosacral roots, except a single case of cervical polyradiculopathy. Of 14 treated patients, nine improved with corticosteroids, laminectomy, or both. Polyradiculopathy complicating sarcoidosis: (1) is uncommon; (2) primarily involves thoracic and lumbar roots; (3) may arise from contiguous, hematogenous, or gravitational nerve root sleeve seeding; (4) may be asymptomatic; and (5) may improve with corticosteroids. Differential diagnosis of weakness in patients with sarcoidosis should include nerve root involvement from the primary process by direct sarcoid involvement.
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I n Europe, Borrelia burgdo@ infection causes a severe, Predominantly axonal polyradiculoneuropathy that is typically accompanied by cranial neuropathy and lymphocytic meningitis (Bannwarth's or Garin-Bujadoux-Bannwarth syndrome) .','' Although a similar clinical syndrome occurs in the U.S.,6,7 this
A 53-year-old man developed progressive sensory disturbance and weakness in the legs, sphincter disturbance, back pain, systemic symptoms, and pancytopenia. Electrophysiological tests indicated a widespread lumbosacral polyradiculopathy. Spinal magnetic resonance imaging and routine cerebrospinal fl