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Polyposis: The Peutz-Jeghers syndrome

✍ Scribed by A. D. Spigelman; P. Arese; Mr. R. K. S. Phillips


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
357 KB
Volume
82
Category
Article
ISSN
0007-1323

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✦ Synopsis


Abstract

The classical pigmentation of Peutz-Jeghers syndrome distinguishes it immediately from the other polyposis syndromes. Less widely appreciated than this most obvious manifestation are the pitfalls in management presented by the risk of cancer and by the performance of multiple laparotomies that also characterize this condition. An outline of these risks and an approach that minimizes them is presented.


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The diagnosis of Peutz-Jeghers syndrome is based on the occurrence of hamartomatous gastrointestinal polyps and perioral pigment spots. In view of the development of hamartomatous polyps in several syndromes and the variability of pigment spots in Peutz-Jeghers patients, identification of affected i