𝔖 Bobbio Scriptorium
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Polyol Peptidomimetics

✍ Scribed by Armin Geyer; Frank Moser


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
481 KB
Volume
2000
Category
Article
ISSN
1434-193X

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New Polyol Syntheses
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1,3,5,…︁-Polyol structures are characteristic components of polyene macrolide antibiotics such as filipin III (1). Iterative stereoselective alkylation of lithiated cyanohydrin acetonides and subsequent reductive decyanation is one possibility for the stepwise synthesis of this class of natural prod