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Polyneuropathy with osteosclerotic myeloma — POEMS syndrome

✍ Scribed by Aleksandra Vidaković; Petar Simić; Nebojša Stojisavljević; Ivo Elezović; Rajko Trikić; Slobodan Apostolski

Publisher
Springer
Year
1992
Tongue
English
Weight
459 KB
Volume
239
Category
Article
ISSN
0340-5354

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📜 SIMILAR VOLUMES

Osteosclerotic myeloma and ‘POEMS’ syndr
Osteosclerotic myeloma and ‘POEMS’ syndrome
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Metabolic bone disease is a major cause of morbidity and mortality in patients suffering from multiple myeloma. This usually results from an imbalance between the osteoclast and osteoblast activity of bone resorption and formation due to the secretion of an osteoclast-activating factor by the myelom

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Multiple myeloma associated with diffuse osteosclerotic bone lesions: A clinical entity distinct from osteosclerotic myeloma (POEMS syndrome)
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Multiple myeloma usually is characterized by the development of lytic bone lesions. Osteosclerotic myeloma is a rare entity characterized by a single or multiple osteosclerotic bone lesions and often accompanied by a demyelinating polyneuropathy. Multiple myeloma associated with widespread osteoscle

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Therapeutic trial of plasma exchange in osteosclerotic myeloma associated with the poems syndrome
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A patient with osteosclerotic myeloma and POEMS syndrome, unresponsive to pulse prednisone and melphalan therapy, was admitted to the hospital for a trial of plasma exchange therapy. The presentation included IgG lambda monoclonal gammopathy, peripheral neuropathy. hepatosplenomegaly, hyperpigmentat

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We describe a patient with a 3 year history of progressive polyneuropathy that rendered him severely quadriparetic and bedridden. Work up revealed an IgG lambda monoclonal spike and multifocal osteosclerotic myeloma. Remarkable improvement followed combined treatment with surgical excision, radiatio